Single-Center Investigation of the Pharmacokinetics of WCK 4282 (Cefepime-Tazobactam Combination) in Renal Impairment

WCK 4282 is a combination product of cefepime (FEP) and tazobactam (TAZ) in a 1:1 ratio currently under development for the treatment of multidrug-resistant Gram-negative bacterial infections. We investigated the effect of renal impairment on the pharmacokinetics (PK) and safety of WCK 4282 in 48 su...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Preston, Richard A., Mamikonyan, Grigor, Mastim, Mushtaque, Garg, Dyal, Kemper, Christopher J., Xu, Allan, Yeole, Ravindra, Chavan, Rajesh, Friedland, H. David, Bhatia, Ashima
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2019
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761517/
https://ncbi.nlm.nih.gov/pubmed/31332068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00873-19
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items