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Damage sensing by a Nox-Ask1-MKK3-p38 signaling pathway mediates regeneration in the adult Drosophila midgut

Epithelia are exposed to diverse types of stress and damage from pathogens and the environment, and respond by regenerating. Yet, the proximal mechanisms that sense epithelial damage remain poorly understood. Here we report that p38 signaling is activated in adult Drosophila midgut enterocytes in re...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Patel, Parthive H., Pénalva, Clothilde, Kardorff, Michael, Roca, Marianne, Pavlović, Bojana, Thiel, Anja, Teleman, Aurelio A., Edgar, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761285/
https://ncbi.nlm.nih.gov/pubmed/31554796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12336-w
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