The Toxoplasma Vacuolar H(+)-ATPase Regulates Intracellular pH and Impacts the Maturation of Essential Secretory Proteins

Vacuolar-proton ATPases (V-ATPases) are conserved complexes that couple the hydrolysis of ATP to the pumping of protons across membranes. V-ATPases are known to play diverse roles in cellular physiology. We studied the Toxoplasma gondii V-ATPase complex and discovered a dual role of the pump in prot...

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Foilsithe in:Cell Rep
Main Authors: Stasic, Andrew J., Chasen, Nathan M., Dykes, Eric J., Vella, Stephen A., Asady, Beejan, Starai, Vincent J., Moreno, Silvia N.J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760873/
https://ncbi.nlm.nih.gov/pubmed/31091451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.04.038
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