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The Toxoplasma Vacuolar H(+)-ATPase Regulates Intracellular pH and Impacts the Maturation of Essential Secretory Proteins
Vacuolar-proton ATPases (V-ATPases) are conserved complexes that couple the hydrolysis of ATP to the pumping of protons across membranes. V-ATPases are known to play diverse roles in cellular physiology. We studied the Toxoplasma gondii V-ATPase complex and discovered a dual role of the pump in prot...
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| Udgivet i: | Cell Rep |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6760873/ https://ncbi.nlm.nih.gov/pubmed/31091451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.04.038 |
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