Epstein-Barr virus subverts mevalonate and fatty acid pathways to promote infected B-cell proliferation and survival

Epstein-Barr virus (EBV) causes infectious mononucleosis and is associated with multiple human malignancies. EBV drives B-cell proliferation, which contributes to the pathogenesis of multiple lymphomas. Yet, knowledge of how EBV subverts host biosynthetic pathways to transform resting lymphocytes in...

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Publicat a:PLoS Pathog
Autors principals: Wang, Liang Wei, Wang, Zhonghao, Ersing, Ina, Nobre, Luis, Guo, Rui, Jiang, Sizun, Trudeau, Stephen, Zhao, Bo, Weekes, Michael P., Gewurz, Benjamin E.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760809/
https://ncbi.nlm.nih.gov/pubmed/31518366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008030
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