Stable pantothenamide bioisosteres: novel antibiotics for Gram-positive bacteria

The emergence of multidrug resistant bacteria has prioritized the development of new antibiotics. N-substituted pantothenamides, analogs of the natural compound pantetheine, were reported to target bacterial coenzyme A biosynthesis, but these compounds have never reached the clinic due to their inst...

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Xehetasun bibliografikoak
Argitaratua izan da:J Antibiot (Tokyo)
Egile Nagusiak: Jansen, Patrick A. M., van der Krieken, Danique A., Botman, Peter N. M., Blaauw, Richard H., Cavina, Lorenzo, Raaijmakers, Eline M., de Heuvel, Erik, Sandrock, Julia, Pennings, Lian J., Hermkens, Pedro H. H., Zeeuwen, Patrick L. J. M., Rutjes, Floris P. J. T., Schalkwijk, Joost
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760626/
https://ncbi.nlm.nih.gov/pubmed/31171848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41429-019-0196-6
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