Genome‐Wide Meta‐Analysis of Blood Pressure Response to β(1)‐Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies)

BACKGROUND: There exists a wide interindividual variability in blood pressure (BP) response to β(1)‐blockers. To identify the genetic determinants of this variability, we performed a pharmacogenomic genome‐wide meta‐analysis of genetic variants influencing β(1)‐blocker BP response. METHODS AND RESUL...

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Pubblicato in:J Am Heart Assoc
Autori principali: Singh, Sonal, Warren, Helen R., Hiltunen, Timo P., McDonough, Caitrin W., El Rouby, Nihal, Salvi, Erika, Wang, Zhiying, Garofalidou, Tatiana, Fyhrquist, Frej, Kontula, Kimmo K., Glorioso, Valeria, Zaninello, Roberta, Glorioso, Nicola, Pepine, Carl J., Munroe, Patricia B., Turner, Stephan T., Chapman, Arlene B., Boerwinkle, Eric, Johnson, Julie A., Gong, Yan, Cooper‐DeHoff, Rhonda M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Systematic Review and Meta‐analysis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759913/
https://ncbi.nlm.nih.gov/pubmed/31423876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.013115
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