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Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B

[Image: see text] In response to the growing threat posed by antibiotic-resistant bacterial strains, extensive research is currently focused on developing antimicrobial agents that target lipid II, a vital precursor in the biosynthesis of bacterial cell walls. The lantibiotic nisin and related pepti...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Dickman, Rachael, Mitchell, Serena A., Figueiredo, Angelo M., Hansen, D. Flemming, Tabor, Alethea B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759747/
https://ncbi.nlm.nih.gov/pubmed/31464129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b01253
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