Chronic dosing with metformin plus bosentan decreases in vitro pulmonary artery contraction from isolated arteries in adults with pulmonary hypertension

Introduction: Pulmonary arterial hypertension (PAH) specific drug therapy using bosentan has significantly improved quality of life and survival, although PAH is still an incurable disease. Recent studies suggest metformin may have additional treatment benefits in PAH. We therefore investigated in v...

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Dades bibliogràfiques
Publicat a:J Cardiovasc Thorac Res
Autors principals: Liao, Shutan, Li, Dongsheng, Hui, Zheng, McLachlan, Craig S, Zhang, Yang
Format: Artigo
Idioma:Inglês
Publicat: Tabriz University of Medical Sciences 2019
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759611/
https://ncbi.nlm.nih.gov/pubmed/31579458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/jcvtr.2019.32
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