Chronic dosing with metformin plus bosentan decreases in vitro pulmonary artery contraction from isolated arteries in adults with pulmonary hypertension

Introduction: Pulmonary arterial hypertension (PAH) specific drug therapy using bosentan has significantly improved quality of life and survival, although PAH is still an incurable disease. Recent studies suggest metformin may have additional treatment benefits in PAH. We therefore investigated in v...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cardiovasc Thorac Res
Prif Awduron: Liao, Shutan, Li, Dongsheng, Hui, Zheng, McLachlan, Craig S, Zhang, Yang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Tabriz University of Medical Sciences 2019
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759611/
https://ncbi.nlm.nih.gov/pubmed/31579458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/jcvtr.2019.32
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