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Lower Doses of Bosentan in Combination With Sildenafil Might be Beneficial in Pulmonary Arterial Hypertension

BACKGROUND: Endothelin-receptor-antagonist, bosentan, has been found to improve the functional capacity and cardiopulmonary hemodynamics in Pulmonary Arterial Hypertension (PAH). Clinical trials have shown the preferable dosage of 125 mg, twice daily, regarding both efficacy and safety. OBJECTIVES:...

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Detalhes bibliográficos
Publicado no:Res Cardiovasc Med
Main Authors: Amin, Ahmad, Mohamadifar, Arezoo, Taghavi, Sepideh, Naderi, Nasim, Sadeghi, Hosnolah
Formato: Artigo
Idioma:Inglês
Publicado em: Kowsar 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588707/
https://ncbi.nlm.nih.gov/pubmed/26436071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5812/cardiovascmed.26487v2
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