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De novo design of selective membrane-active peptides via enzymatic control of their conformational bias on the cell surface
Selectively targeting the membrane-perturbing potential of peptides towards a distinct cellular phenotype has been an elusive, but powerful property that allows one to target distinct populations of cells. We report the de novo design of a new class of peptide whose potential to perturb cellular mem...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6759387/ https://ncbi.nlm.nih.gov/pubmed/31268617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201902470 |
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