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De novo design of selective membrane-active peptides via enzymatic control of their conformational bias on the cell surface

Selectively targeting the membrane-perturbing potential of peptides towards a distinct cellular phenotype has been an elusive, but powerful property that allows one to target distinct populations of cells. We report the de novo design of a new class of peptide whose potential to perturb cellular mem...

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Dades bibliogràfiques
Publicat a:Angew Chem Int Ed Engl
Autors principals: Shi, Junfeng, Schneider, Joel P.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759387/
https://ncbi.nlm.nih.gov/pubmed/31268617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201902470
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