Folic Acid Deficiency and Homocysteine Impair DNA Repair in Hippocampal Neurons and Sensitize Them to Amyloid Toxicity in Experimental Models of Alzheimer's Disease

Recent epidemiological and clinical data suggest that persons with low folic acid levels and elevated homocysteine levels are at increased risk of Alzheimer's disease (AD), but the underlying mechanism is unknown. We tested the hypothesis that impaired one-carbon metabolism resulting from folic...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Kruman, Inna I., Kumaravel, T. S., Lohani, Althaf, Pedersen, Ward A., Cutler, Roy G., Kruman, Yuri, Haughey, Norman, Lee, Jaewon, Evans, Michele, Mattson, Mark P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2002
Onderwerpen:
ARTICLE
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758871/
https://ncbi.nlm.nih.gov/pubmed/11880504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-05-01752.2002
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items