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G-Protein-Gated Potassium Channels Containing Kir3.2 and Kir3.3 Subunits Mediate the Acute Inhibitory Effects of Opioids on Locus Ceruleus Neurons

Acute opioid administration causes hyperpolarization of locus ceruleus (LC) neurons. A G-protein-gated, inwardly rectifying potassium (GIRK/K(G)) conductance and a cAMP-dependent cation conductance have both been implicated in this effect; the relative contribution of each conductance remains contro...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Torrecilla, Maria, Marker, Cheryl L., Cintora, Stephanie C., Stoffel, Markus, Williams, John T., Wickman, Kevin
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758804/
https://ncbi.nlm.nih.gov/pubmed/12040038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-11-04328.2002
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