Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies

Inhibition of Carbonic Anhydrases (CAs) has been clinically exploited for many decades for a variety of therapeutic applications. Within a research project aimed at developing novel classes of CA inhibitors (CAIs) with a proper selectivity for certain isoforms, a series of derivatives featuring the...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Wydane w:J Enzyme Inhib Med Chem
Główni autorzy: Milite, Ciro, Amendola, Giorgio, Nocentini, Alessio, Bua, Silvia, Cipriano, Alessandra, Barresi, Elisabetta, Feoli, Alessandra, Novellino, Ettore, Da Settimo, Federico, Supuran, Claudiu T., Castellano, Sabrina, Cosconati, Sandro, Taliani, Sabrina
Format: Artigo
Język:Inglês
Wydane: Taylor & Francis 2019
Hasła przedmiotowe:
Research Paper
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758606/
https://ncbi.nlm.nih.gov/pubmed/31537132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1666836
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