Estrogen and Aging Affect the Subcellular Distribution of Estrogen Receptor-α in the Hippocampus of Female Rats

Estrogen replacement increases both the number of dendritic spines and the density of axospinous synapses in the hippocampal CA1 region in young rats, yet this is attenuated in aged rats. The estrogen receptor-α (ER-α) is localized within select spines of CA1 pyramidal cells in young animals and thu...

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Pubblicato in:J Neurosci
Autori principali: Adams, Michelle M., Fink, Susan E., Shah, Ravi A., Janssen, William G. M., Hayashi, Shinji, Milner, Teresa A., McEwen, Bruce S., Morrison, John H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758372/
https://ncbi.nlm.nih.gov/pubmed/11978836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-09-03608.2002
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