Coincident Elevation of cAMP and Calcium Influx by PACAP-27 Synergistically Regulates Vasoactive Intestinal Polypeptide Gene Transcription through a Novel PKA-Independent Signaling Pathway

Pituitary adenylate cyclase-activating polypeptide (PACAP) causes calcium influx, intracellular calcium release, and elevation of cAMP in chromaffin cells. Calcium influx is required for PACAP-stimulated secretion of catecholamines and neuropeptides. The role of cAMP elevation in the action of PACAP...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Hamelink, Carol, Lee, Hyeon-Woo, Chen, Yun, Grimaldi, Maurizio, Eiden, Lee E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2002
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758207/
https://ncbi.nlm.nih.gov/pubmed/12097482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-13-05310.2002
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