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Neuroprotection by Hypoxic Preconditioning Requires Sequential Activation of Vascular Endothelial Growth Factor Receptor and Akt

Hypoxic preconditioning provides protection against ischemic brain lesions in animal models of cerebral ischemia–hypoxia. To analyze the underlying molecular mechanisms, we developed an invitro model of hypoxic neuroprotection in cerebellar granule neurons (CGN) by reducing the oxygen tension to 1–5...

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Dettagli Bibliografici
Pubblicato in:J Neurosci
Autori principali: Wick, Antje, Wick, Wolfgang, Waltenberger, Johannes, Weller, Michael, Dichgans, Johannes, Schulz, Jörg B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758162/
https://ncbi.nlm.nih.gov/pubmed/12151519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-15-06401.2002
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