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Neuroprotection by Hypoxic Preconditioning Requires Sequential Activation of Vascular Endothelial Growth Factor Receptor and Akt

Hypoxic preconditioning provides protection against ischemic brain lesions in animal models of cerebral ischemia–hypoxia. To analyze the underlying molecular mechanisms, we developed an invitro model of hypoxic neuroprotection in cerebellar granule neurons (CGN) by reducing the oxygen tension to 1–5...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Wick, Antje, Wick, Wolfgang, Waltenberger, Johannes, Weller, Michael, Dichgans, Johannes, Schulz, Jörg B.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758162/
https://ncbi.nlm.nih.gov/pubmed/12151519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-15-06401.2002
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