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No Ligand Binding in the GB2 Subunit of the GABA(B)Receptor Is Required for Activation and Allosteric Interaction between the Subunits
The GABA(B) receptor plays important roles in the tuning of many synapses. Although pharmacological differences have been observed between various GABA(B)-mediated effects, a single GABA(B) receptor composed of two subunits (GB1 and GB2) has been identified. Although GB1 binds GABA, GB2 plays a crit...
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| Publicado en: | J Neurosci |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Society for Neuroscience
2002
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6757956/ https://ncbi.nlm.nih.gov/pubmed/12196556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-17-07352.2002 |
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