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Group I Metabotropic Glutamate Receptor (mGluR)-Dependent Long-Term Depression Mediated via p38 Mitogen-Activated Protein Kinase Is Inhibited by Previous High-Frequency Stimulation and Activation of mGluRs and Protein Kinase C in the Rat Dentate Gyrus In Vitro

The induction of synaptic plasticity is known to be influenced by the previous history of the synapse, a process termed metaplasticity. Here we demonstrate a novel metaplasticity in which group I metabotropic glutamate receptor (mGluR)-dependent long-term depression (LTD) of synaptic transmission is...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Rush, Anthony M., Wu, Jianqun, Rowan, Michael J., Anwyl, Roger
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757950/
https://ncbi.nlm.nih.gov/pubmed/12122073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-14-06121.2002
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