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A Novel FERM Domain Including Guanine Nucleotide Exchange Factor Is Involved in Rac Signaling and Regulates Neurite Remodeling

The Rho family of small GTPases, key regulators of the actin cytoskeleton in eukaryotic cells from yeast to human, is implicated in the control of neuronal morphology. Guanine nucleotide exchange factors (GEFs) are upstream positive regulators of Rho GTPases and integrate extracellular signaling for...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Kubo, Tateki, Yamashita, Toshihide, Yamaguchi, Atsushi, Sumimoto, Hideki, Hosokawa, Ko, Tohyama, Masaya
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757789/
https://ncbi.nlm.nih.gov/pubmed/12351724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-19-08504.2002
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