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A Novel FERM Domain Including Guanine Nucleotide Exchange Factor Is Involved in Rac Signaling and Regulates Neurite Remodeling

The Rho family of small GTPases, key regulators of the actin cytoskeleton in eukaryotic cells from yeast to human, is implicated in the control of neuronal morphology. Guanine nucleotide exchange factors (GEFs) are upstream positive regulators of Rho GTPases and integrate extracellular signaling for...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Kubo, Tateki, Yamashita, Toshihide, Yamaguchi, Atsushi, Sumimoto, Hideki, Hosokawa, Ko, Tohyama, Masaya
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757789/
https://ncbi.nlm.nih.gov/pubmed/12351724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-19-08504.2002
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