Dopamine Induces a PI3-Kinase-Independent Activation of Akt in Striatal Neurons: A New Route to cAMP Response Element-Binding Protein Phosphorylation

Akt is classically described as a prosurvival serine/threonine kinase activated in response to trophic factors. After activation by phosphoinositide 3-kinase (PI3-kinase), it can translocate to the nucleus where it promotes specific genetic programs by catalyzing phosphorylation of transcription fac...

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Publicado en:J Neurosci
Autores principales: Brami-Cherrier, Karen, Valjent, Emmanuel, Garcia, Marta, Pagès, Christiane, Hipskind, Robert A., Caboche, Jocelyne
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2002
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ARTICLE
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757682/
https://ncbi.nlm.nih.gov/pubmed/12388598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-20-08911.2002
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