Synaptic Vesicle Depletion Correlates with Attenuated Synaptic Responses to Prolonged Repetitive Stimulation in Mice Lacking α-Synuclein

Although the mutation of α-synuclein, a protein associated with presynaptic vesicles, is implicated in the etiology and pathogenesis of Parkinson's disease, the biological function of the normal protein is unknown. Mice that lack α-synuclein have been generated by homologous recombination in em...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Cabin, Deborah E., Shimazu, Kazuhiro, Murphy, Diane, Cole, Nelson B., Gottschalk, Wolfram, McIlwain, Kellie L., Orrison, Bonnie, Chen, Amy, Ellis, Christopher E., Paylor, Richard, Lu, Bai, Nussbaum, Robert L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2002
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757677/
https://ncbi.nlm.nih.gov/pubmed/12388586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-20-08797.2002
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