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TrkB Gene Transfer Protects Retinal Ganglion Cells from Axotomy-Induced Death In Vivo

Injury-induced downregulation of neurotrophin receptors may limit the response of neurons to trophic factors, compromising their ability to survive. We tested this hypothesis in a model of CNS injury: retinal ganglion cell (RGC) death after transection of the adult rat optic nerve. TrkB mRNA rapidly...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Cheng, Li, Sapieha, Przemyslaw, Kittlerová, Pavla, Hauswirth, William W., Di Polo, Adriana
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757661/
https://ncbi.nlm.nih.gov/pubmed/12019317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-10-03977.2002
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