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Growth-Associated Protein-43 Is Required for Commissural Axon Guidance in the Developing Vertebrate Nervous System

Growth-associated protein-43 (GAP-43) is a major growth cone protein whose phosphorylation by PKC in response to extracellular guidance cues can regulate F-actin behavior. Here we show that 100% of homozygote GAP-43 (−/−) mice failed to form the anterior commissure (AC), hippocampal commissure (HC),...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Shen, Yiping, Mani, Shyamala, Donovan, Stacy L., Schwob, James E., Meiri, Karina F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757587/
https://ncbi.nlm.nih.gov/pubmed/11756507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-01-00239.2002
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