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Activation of Rac GTPase by p75 Is Necessary for c-jun N-Terminal Kinase-Mediated Apoptosis
The neurotrophin receptor p75 can induce apoptosis both in vitro and in vivo. The mechanisms by which p75 induces apoptosis have remained mostly unknown. Here, we report that p75 activates Rac GTPase, which in turn activates c-junN-terminal kinase (JNK), including an injury-specific JNK3, in an NGF-...
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| Yayımlandı: | J Neurosci |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Society for Neuroscience
2002
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6757583/ https://ncbi.nlm.nih.gov/pubmed/11756498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-01-00156.2002 |
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