A carregar...
Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader
[Image: see text] SGK3 is a PX domain containing protein kinase activated at endosomes downstream of class 1 and 3 PI3K family members by growth factors and oncogenic mutations. SGK3 plays a key role in mediating resistance of breast cancer cells to class 1 PI3K or Akt inhibitors, by substituting fo...
Na minha lista:
| Publicado no: | ACS Chem Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical
Society
2019
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6757289/ https://ncbi.nlm.nih.gov/pubmed/31461270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00505 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|