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β-estradiol protects against acidosis-mediated and ischemic neuronal injury by promoting ASIC1a protein degradation

BACKGROUND AND PURPOSE—: Gender differences in the incidence and outcome of stroke have been well documented. The severity of stroke in women is, in general, significantly lower than that in men, which is mediated, at least in part, by the protective effects of β-estradiol. However, the detailed mec...

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Detalhes bibliográficos
Publicado no:Stroke
Main Authors: Zhou, Renpeng, Leng, Tiandong, Yang, Tao, Chen, Feihu, Hu, Wei, Xiong, Zhigang
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756944/
https://ncbi.nlm.nih.gov/pubmed/31412757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.119.025940
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