The effects of focal adhesion kinase and platelet-derived growth factor receptor beta inhibition in a patient-derived xenograft model of primary and metastatic Wilms tumor

Aggressive therapies for patients with metastatic Wilms tumor (WT) with subsequent severe late effects warrant the search for novel therapies. The role of focal adhesion kinase (FAK), a non-receptor tyrosine kinase important in pediatric solid tumor development and progression, has not been examined...

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Vydáno v:Oncotarget
Hlavní autoři: Aye, Jamie M., Stafman, Laura L., Williams, Adele P., Garner, Evan F., Stewart, Jerry E., Anderson, Joshua C., Mruthyunjayappa, Smitha, Waldrop, Mary G., Goolsby, Caroline D., Markert, Hooper R., Quinn, Colin, Marayati, Raoud, Mroczek-Musulman, Elizabeth, Willey, Christopher D., Yoon, Karina J., Whelan, Kimberly F., Beierle, Elizabeth A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756857/
https://ncbi.nlm.nih.gov/pubmed/31565187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27165
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