FTY720 enhances the anti-tumor activity of carboplatin and tamoxifen in a patient-derived xenograft model of ovarian cancer

Ovarian cancer is the fifth leading cause of cancer-related deaths among women in the United States. Although most patients respond to frontline therapy, virtually all patients relapse with chemoresistant disease. This study addresses the hypothesis that carboplatin or tamoxifen + FTY720, a sphingos...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Kreitzburg, Kelly M., Fehling, Samuel C., Landen, Charles N., Gamblin, Tracy L., Vance, Rebecca B., Arend, Rebecca C., Katre, Ashwini A., Oliver, Patsy G., van Waardenburg, Robert C.A.M, Alvarez, Ronald D., Yoon, Karina J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756795/
https://ncbi.nlm.nih.gov/pubmed/30120964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2018.08.015
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