LIPid Intensive Drug therapy for Sepsis Pilot (LIPIDS-P): Phase I/II clinical trial protocol of lipid emulsion therapy for stabilising cholesterol levels in sepsis and septic shock

INTRODUCTION: Sepsis is a life-threatening, dysregulated response to infection. Both high-density lipoprotein and low-density lipoprotein cholesterol should protect against sepsis by several mechanisms; however, for partially unknown reasons, cholesterol levels become critically low in patients with...

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Dettagli Bibliografici
Pubblicato in:BMJ Open
Autori principali: Guirgis, Faheem W, Black, Lauren Page, Rosenthal, Martin Daniel, Henson, Morgan, Ferreira, Jason, Leeuwenburgh, Christiaan, Kalynych, Colleen, Moldawer, Lyle L, Miller, Taylor, Jones, Lisa, Crandall, Marie, Reddy, Srinivasa T, Wu, Samuel S, Moore, Frederick A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2019
Soggetti:
Intensive Care
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756323/
https://ncbi.nlm.nih.gov/pubmed/31537565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2019-029348
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