LIPid Intensive Drug therapy for Sepsis Pilot (LIPIDS-P): Phase I/II clinical trial protocol of lipid emulsion therapy for stabilising cholesterol levels in sepsis and septic shock

INTRODUCTION: Sepsis is a life-threatening, dysregulated response to infection. Both high-density lipoprotein and low-density lipoprotein cholesterol should protect against sepsis by several mechanisms; however, for partially unknown reasons, cholesterol levels become critically low in patients with...

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Detalles Bibliográficos
Publicado en:BMJ Open
Main Authors: Guirgis, Faheem W, Black, Lauren Page, Rosenthal, Martin Daniel, Henson, Morgan, Ferreira, Jason, Leeuwenburgh, Christiaan, Kalynych, Colleen, Moldawer, Lyle L, Miller, Taylor, Jones, Lisa, Crandall, Marie, Reddy, Srinivasa T, Wu, Samuel S, Moore, Frederick A
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2019
Assuntos:
Intensive Care
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756323/
https://ncbi.nlm.nih.gov/pubmed/31537565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2019-029348
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