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Inhibition of esophageal cancer growth through the suppression of PI3K/AKT/mTOR signaling pathway
BACKGROUND: The phosphatidylinositol-3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway is implicated in several cancers. AKT allosteric inhibitor MK2206 and dual PI3K and mTOR inhibitor BEZ235 are promising drug candidates with potential anti-tumor effects. PURPOSE...
Tallennettuna:
| Julkaisussa: | Onco Targets Ther |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Dove
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6756275/ https://ncbi.nlm.nih.gov/pubmed/31571914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S205457 |
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