Invadopodia are chemosensing protrusions that guide cancer cell extravasation to promote brain tropism in metastasis

Invadopodia are cell protrusions that mediate cancer cell extravasation but the microenvironmental cues and signaling factors that induce invadopodia formation during extravasation remain unclear. Using intravital imaging and loss of function experiments, we determined invadopodia contain receptors...

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Détails bibliographiques
Publié dans:Oncogene
Auteurs principaux: Williams, Karla C., Cepeda, Mario A., Javed, Sumreen, Searle, Karlee, Parkins, Katie M., Makela, Ashley V., Hamilton, Amanda M., Soukhtehzari, Sepideh, Kim, Yohan, Tuck, Alan B., Ronald, John A., Foster, Paula J., Chambers, Ann F., Leong, Hon S.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756237/
https://ncbi.nlm.nih.gov/pubmed/30651600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0667-4
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