Depletion of Ars2 inhibits cell proliferation and leukemogenesis in acute myeloid leukemia by modulating the miR-6734-3p/p27 axis

Ars2 is a component of the nuclear cap-binding complex (CBC) that contributes to microRNA biogenesis and is required for cellular proliferation. Little is known regarding the functional role of Ars2 in cell proliferation and leukemogenesis of acute myeloid leukemia. Here, we show that the elevated e...

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Bibliographic Details
Published in:Leukemia
Main Authors: Hu, Xiaoye, Xu, Shuangnian, Chen, Yibiao, Gao, Ziyi, Li, Yunong, Hu, Jinjiao, Huang, Xiuning, Zhang, Yanhao, Jiang, Xiuxing, Li, Lirong, Yang, Chong, Chen, Jieping, Gao, Ning
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756072/
https://ncbi.nlm.nih.gov/pubmed/30518811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0301-z
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