LPLUNC1 stabilises PHB1 by counteracting TRIM21-mediated ubiquitination to inhibit NF-κB activity in nasopharyngeal carcinoma

Long-palate, lung and nasal epithelium clone 1 (LPLUNC1) is a tumour suppressor gene in nasopharyngeal carcinoma (NPC), and low expression of LPLUNC1 is associated with poor prognosis. Our previous study showed that LPLUNC1 upregulates Prohibitin 1 (PHB1), a pleiotropic protein that functions as a t...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Wang, Heran, Zhou, Yujuan, Oyang, Linda, Han, Yaqian, Xia, Longzheng, Lin, Jingguan, Tang, Yanyan, Su, Min, Tan, Shiming, Tian, Yutong, Chen, Xiaoyan, Luo, Xia, Liang, Jiaxin, Rao, Shan, Wang, Ying, Xiong, Wei, Zeng, Zhaoyang, Wang, Hui, Li, Guiyuan, Liao, Qianjin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756001/
https://ncbi.nlm.nih.gov/pubmed/30886235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0778-6
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