Diallyl disulfide inhibits colon cancer metastasis by suppressing Rac1-mediated epithelial-mesenchymal transition

BACKGROUND: Prevention of epithelial-mesenchymal transition (EMT) provides a novel treatment strategy for tumor metastasis. Our previous studies have shown that diallyl disulfide (DADS) inhibits Ras related C3 botulinum toxin substrate1 (Rac1) expression, being a potential agent that suppresses migr...

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Xia, Longzheng, Lin, Jingguan, Su, Jian, Oyang, Linda, Wang, Heran, Tan, Shiming, Tang, Yanyan, Chen, Xiaoyan, Liu, Wenbin, Luo, Xia, Tian, Yutong, Liang, Jiaxin, Su, Qi, Liao, Qianjin, Zhou, Yujuan
Format: Artigo
Language:Inglês
Published: Dove 2019
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6645609/
https://ncbi.nlm.nih.gov/pubmed/31410018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S208738
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