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Functional analyses of ancestral thioredoxins provide insights into their evolutionary history

Thioredoxin (Trx) is a conserved, cytosolic reductase in all known organisms. The enzyme receives two electrons from NADPH via thioredoxin reductase (TrxR) and passes them on to multiple cellular reductases via disulfide exchange. Despite the ubiquity of thioredoxins in all taxa, little is known abo...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Napolitano, Silvia, Reber, Robin J., Rubini, Marina, Glockshuber, Rudi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755812/
https://ncbi.nlm.nih.gov/pubmed/31366732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009718
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