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Functional analyses of ancestral thioredoxins provide insights into their evolutionary history

Thioredoxin (Trx) is a conserved, cytosolic reductase in all known organisms. The enzyme receives two electrons from NADPH via thioredoxin reductase (TrxR) and passes them on to multiple cellular reductases via disulfide exchange. Despite the ubiquity of thioredoxins in all taxa, little is known abo...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Napolitano, Silvia, Reber, Robin J., Rubini, Marina, Glockshuber, Rudi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755812/
https://ncbi.nlm.nih.gov/pubmed/31366732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009718
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