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An engineered mutant of a host phospholipid synthesis gene inhibits viral replication without compromising host fitness

Viral infections universally rely on numerous hijacked host factors to be successful. It is therefore possible to control viral infections by manipulating host factors that are critical for viral replication. Given that host genes may play essential roles in certain cellular processes, any successfu...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: He, Guijuan, Zhang, Zhenlu, Sathanantham, Preethi, Zhang, Xin, Wu, Zujian, Xie, Lianhui, Wang, Xiaofeng
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755795/
https://ncbi.nlm.nih.gov/pubmed/31362985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007051
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