Host Pah1p phosphatidate phosphatase limits viral replication by regulating phospholipid synthesis

Replication of positive-strand RNA viruses [(+)RNA viruses] takes place in membrane-bound viral replication complexes (VRCs). Formation of VRCs requires virus-mediated manipulation of cellular lipid synthesis. Here, we report significantly enhanced brome mosaic virus (BMV) replication and much impro...

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Dettagli Bibliografici
Pubblicato in:PLoS Pathog
Autori principali: Zhang, Zhenlu, He, Guijuan, Han, Gil-Soo, Zhang, Jiantao, Catanzaro, Nicholas, Diaz, Arturo, Wu, Zujian, Carman, George M., Xie, Lianhui, Wang, Xiaofeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916857/
https://ncbi.nlm.nih.gov/pubmed/29649282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006988
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