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GSK343 induces autophagy and downregulates the AKT/mTOR signaling pathway in pancreatic cancer cells
Pancreatic cancer is a common malignancy that has a poor prognosis and limited therapeutic options. Enhancer of zeste homolog 2 (EZH2) serves a key role in the progression of different types of cancers. The effect of GSK343 (a competitive inhibitor of EZH2) on pancreatic cancer cells was assessed in...
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| Publicado no: | Exp Ther Med |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6755448/ https://ncbi.nlm.nih.gov/pubmed/31572509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7845 |
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