Apolipoprotein E-Mimetic Peptide COG1410 Enhances Retinal Ganglion Cell Survival by Attenuating Inflammation and Apoptosis Following TONI

Vision loss after traumatic optic nerve injury (TONI) is considered irreversible because of the retrograde loss of retinal ganglion cells (RGCs), which undergo inflammation and apoptosis. Previous studies have shown that COG1410, a mimic peptide derived from the apolipoprotein E (apoE) receptor bind...

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Detalles Bibliográficos
Publicado en:Front Neurosci
Main Authors: Kuai, Li, Peng, Jianhua, Jiang, Yong, Zheng, Zheng, Zhou, Xiyuan
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755331/
https://ncbi.nlm.nih.gov/pubmed/31607842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00980
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