Apolipoprotein E-Mimetic Peptide COG1410 Enhances Retinal Ganglion Cell Survival by Attenuating Inflammation and Apoptosis Following TONI

Vision loss after traumatic optic nerve injury (TONI) is considered irreversible because of the retrograde loss of retinal ganglion cells (RGCs), which undergo inflammation and apoptosis. Previous studies have shown that COG1410, a mimic peptide derived from the apolipoprotein E (apoE) receptor bind...

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Détails bibliographiques
Publié dans:Front Neurosci
Auteurs principaux: Kuai, Li, Peng, Jianhua, Jiang, Yong, Zheng, Zheng, Zhou, Xiyuan
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Neuroscience
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755331/
https://ncbi.nlm.nih.gov/pubmed/31607842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00980
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