Apolipoprotein E-Mimetic Peptide COG1410 Enhances Retinal Ganglion Cell Survival by Attenuating Inflammation and Apoptosis Following TONI

Vision loss after traumatic optic nerve injury (TONI) is considered irreversible because of the retrograde loss of retinal ganglion cells (RGCs), which undergo inflammation and apoptosis. Previous studies have shown that COG1410, a mimic peptide derived from the apolipoprotein E (apoE) receptor bind...

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Udgivet i:Front Neurosci
Main Authors: Kuai, Li, Peng, Jianhua, Jiang, Yong, Zheng, Zheng, Zhou, Xiyuan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755331/
https://ncbi.nlm.nih.gov/pubmed/31607842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00980
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