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AhR Activation Leads to Massive Mobilization of Myeloid-Derived Suppressor Cells with Immunosuppressive Activity through Regulation of CXCR2 and MicroRNA miR-150-5p and miR-543-3p That Target Anti-Inflammatory Genes

The compound 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), an environmental contaminant, is a potent ligand for aryl hydrocarbon receptor (AhR). In the current study, we made an exciting observation that naive C57BL/6 mice that were exposed i.p. to TCDD showed massive mobilization of myeloid-derived s...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Immunol
Κύριοι συγγραφείς: Neamah, Wurood Hantoosh, Singh, Narendra P., Alghetaa, Hasan, Abdulla, Osama A., Chatterjee, Saurabh, Busbee, Philip B., Nagarkatti, Mitzi, Nagarkatti, Prakash
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: AAI 2019
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755129/
https://ncbi.nlm.nih.gov/pubmed/31492743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900291
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