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Liquid Biopsy Detects Relapse Five Months Earlier than Regular Clinical Follow-Up and Guides Targeted Treatment in Breast Cancer

Genetic alterations in circulating tumor DNA (ctDNA) are an emerging biomarker for the early detection of relapse and have the potential to guide targeted treatment. ctDNA analysis is often performed by droplet digital PCR; however, next-generation sequencing (NGS) allows multigene testing without h...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Case Rep Oncol Med
Hauptverfasser: Cheng, Fiona Tsui-Fen, Lapke, Nina, Wu, Chin-Chu, Lu, Yen-Jung, Chen, Shu-Jen, Yu, Pei-Ning, Liu, Yen-Ting, Tan, Kien Thiam
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754891/
https://ncbi.nlm.nih.gov/pubmed/31583146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6545298
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