Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and adaptation to growth environments

Glioblastoma multiforme (GBM) is the most deadly brain tumor, and currently lacks effective treatment options. Brain tumor-initiating cells (BTICs) and orthotopic xenografts are widely used in investigating GBM biology and new therapies for this aggressive disease. However, the genomic characteristi...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Proc Natl Acad Sci U S A
Main Authors: Shen, Yaoqing, Grisdale, Cameron J., Islam, Sumaiya A., Bose, Pinaki, Lever, Jake, Zhao, Eric Y., Grinshtein, Natalie, Ma, Yussanne, Mungall, Andrew J., Moore, Richard A., Lun, Xueqing, Senger, Donna L., Robbins, Stephen M., Wang, Alice Yijun, MacIsaac, Julia L., Kobor, Michael S., Luchman, H. Artee, Weiss, Samuel, Chan, Jennifer A., Blough, Michael D., Kaplan, David R., Cairncross, J. Gregory, Marra, Marco A., Jones, Steven J. M.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2019
נושאים:
PNAS Plus
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754609/
https://ncbi.nlm.nih.gov/pubmed/31471491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1813495116
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