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Class Id ribonucleotide reductase utilizes a Mn(2)(IV,III) cofactor and undergoes large conformational changes on metal loading

Outside of the photosynthetic machinery, high-valent manganese cofactors are rare in biology. It was proposed that a recently discovered subclass of ribonucleotide reductase (RNR), class Id, is dependent on a Mn(2)(IV,III) cofactor for catalysis. Class I RNRs consist of a substrate-binding component...

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Detalhes bibliográficos
Publicado no:J Biol Inorg Chem
Main Authors: Rozman Grinberg, Inna, Berglund, Sigrid, Hasan, Mahmudul, Lundin, Daniel, Ho, Felix M., Magnuson, Ann, Logan, Derek T., Sjöberg, Britt-Marie, Berggren, Gustav
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754362/
https://ncbi.nlm.nih.gov/pubmed/31414238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-019-01697-8
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