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Bicoid-Dependent Activation of the Target Gene hunchback Requires a Two-Motif Sequence Code in a Specific Basal Promoter

In complex genetic loci, individual enhancers interact most often with specific basal promoters. Here we investigate the activation of the Bicoid target gene hunchback (hb), which contains two basal promoters (P1 and P2). Early in embryogenesis, P1 is silent, while P2 is strongly activated. In vivo...

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Publicat a:Mol Cell
Autors principals: Ling, Jia, Umezawa, Kristaley Yui, Scott, Theresa, Small, Stephen
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754290/
https://ncbi.nlm.nih.gov/pubmed/31402096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.06.038
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